Cholera is an acute diarrhoeal infection caused by the bacterium Vibrio cholera of serogroups O1 or O139. Humans are the only relevant reservoir, even though Vibrios can survive for a long time in coastal waters contaminated by human excreta.
Meningococcal disease is caused by Neisseria meningitidis, a bacterium with human carriers as the only reservoir. It is carried in the nose, where it can remain for long periods without producing symptoms.
Rabies is a disease caused by rabies virus (a Lyssavirus). Every year, a small number of cases of rabies is reported in Europe - travel-related or autochthonous.
Pertussis, also known as whooping cough, is a highly contagious acute respiratory infection, caused by the bacterium Bordetella pertussis. The disease is characterised by a severe cough, which can last two months or even longer.
Yellow fever (YF) cause a wide spectrum of symptoms, from mild to fatal. In severe cases there may be spontaneous haemorrhage. Mortality of these clinical cases can be as high as 80%, on a par with Ebola, Marburg and other haemorrhagic viral infections.
Hepatitis B is a liver disease that results from infection with the hepatitis B virus (HBV) and is spread through contact with infected body fluids or blood products.
Diphtheria is spread through droplets from coughing or sneezing. Most often the disease causes a sore throat and low grade fever in the first few days of the illness.
Rubella is a mild febrile rash illness caused by rubella virus. It is transmitted from person to person via droplets (the virus is present in throat secretions). It affects mainly, but not only, children and when pregnant women are infected, it may result in malformation of the foetus. Humans are the only reservoir of infection.