The heptavalent pneumococcal conjugate vaccine (PCV7) targets seven of the more than 92 pneumococcal serotypes. Concerns have been raised that non-vaccine serotypes (NVTs) could increase in prevalence and reduce the benefits of vaccination. Indeed, among asymptomatic carriers, the prevalence of NVTs has increased substantially, and consequently, there has been little or no net change in the bacterial carriage prevalence.
The authors analyzed data from hospital admissions and enhanced mumps surveillance to assess mumps complications during the largest mumps outbreak in England and Wales, 2004–2005, and their association with mumps vaccination. When compared with non-outbreak periods, the outbreak was associated with a clear increase in hospitalized patients with orchitis, meningitis and pancreatitis. Routine mumps surveillance and hospital data showed that 6.1% of mumps patients were hospitalized, 4.4% had orchitis, 0.35% meningitis and 0.33% pancreatitis.
The agreed document will now go to WHO’s governing body the World Health Assembly in May 2011 (16-24 May) with a report from the Group and a Resolution strongly recommending adoption.
This study estimates the burden of disease of the pandemic influenza A(H1N1)2009 virus in the Netherlands during the pandemic season and compares it to the overall burden of disease by calculating Disability Adjusted Life Years (DALYs), a composite measure that combines incidence, sequelae and mortality associated with a disease, taking duration and severity into account.
The United Kingdom has recently published a new influenza pandemic strategy for consultation with key stakeholders. The consultation runs to June 2011 and is the last stage before formal adoption.
Today, the impact of vaccines on Public Health is at the centre of the discussions in the conference organised by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) in Prague. This conference brought together experts to debate the many-sided correlations between vaccines, medicine and society at the dawn of the third millennium.
A four-fold increased incidence of narcolepsy in vaccinated children/adolescents compared to unvaccinated children was observed in this register-based cohort study.
2 papers are reviewed: A Novel Risk Factor for a Novel Virus: Obesity and 2009 Pandemic Influenza A (H1N1) and Morbid Obesity as a Risk Factor for Hospitalization and Death Due to 2009 Pandemic Influenza A(H1N1) Disease.