Using surveillance data obtained from 21,888 imported Plasmodium falciparum cases in France during 1996-2003, factors independently associated with severe malaria (832 cases; ≈3.8%) were older age, European origin, travel to eastern Africa, absence of chemoprophylaxis, initial visit to a general practitioner, time to diagnosis of 4 to 12 days, and diagnosis during the fall-winter season.
This study describes the outcome of 25 travellers with severe malaria who returned from malaria-endemic regions and were treated at 7 centres in Europe with intravenous artesunate. Among these 25 patients, one child and 24 adults (mean ± SD age 44.1 ± 16.1 years), 10 patients received the dosing regimen for artesunate initially recommended by WHO and 11 received artesunate, 2.4 mg/kg/dose.
ECDC was pleased that the Government of Romania extended an invite to meet health care workers who are working with the Roma population. ECDC Director, Marc Sprenger, as head of the delegation shares three lesson.
During a recent country visit to Romania, ECDC emphasised the key issues for TB control. Following the invitation of the Romania Ministry of Health, ECDC disease experts, led by ECDC Director Marc Sprenger, visited the Marius Nasta Institute, which historically has been in the front line for TB control in the country.
The heptavalent pneumococcal conjugate vaccine (PCV7) targets seven of the more than 92 pneumococcal serotypes. Concerns have been raised that non-vaccine serotypes (NVTs) could increase in prevalence and reduce the benefits of vaccination. Indeed, among asymptomatic carriers, the prevalence of NVTs has increased substantially, and consequently, there has been little or no net change in the bacterial carriage prevalence.
The authors analyzed data from hospital admissions and enhanced mumps surveillance to assess mumps complications during the largest mumps outbreak in England and Wales, 2004–2005, and their association with mumps vaccination. When compared with non-outbreak periods, the outbreak was associated with a clear increase in hospitalized patients with orchitis, meningitis and pancreatitis. Routine mumps surveillance and hospital data showed that 6.1% of mumps patients were hospitalized, 4.4% had orchitis, 0.35% meningitis and 0.33% pancreatitis.
The agreed document will now go to WHO’s governing body the World Health Assembly in May 2011 (16-24 May) with a report from the Group and a Resolution strongly recommending adoption.
This study estimates the burden of disease of the pandemic influenza A(H1N1)2009 virus in the Netherlands during the pandemic season and compares it to the overall burden of disease by calculating Disability Adjusted Life Years (DALYs), a composite measure that combines incidence, sequelae and mortality associated with a disease, taking duration and severity into account.
The United Kingdom has recently published a new influenza pandemic strategy for consultation with key stakeholders. The consultation runs to June 2011 and is the last stage before formal adoption.