In 2021, 30 EU/EEA countries reported 3 864 cases of hepatitis A (Table 1). The EU/EEA notification rate was 0.9 cases per 100 000 population. In 2021, both the lowest number of reported cases and the lowest notification rate were reported since the beginning of EU-level hepatitis A surveillance in 2007. The total number of hepatitis A cases reported in EU/EEA countries in 2021 represented a decrease of 65.7% and 12.3% compared to 2019 and 2020, respectively.
Clusters and outbreaks of hepatitis A virus (HAV) genotype IB with four unique but closely related HAV sequences have been reported in six European Union (EU) countries and in the United Kingdom (UK).