Rotaviruses are the single most important cause of severe diarrhoeal illness in infants and young children worldwide. By the age of five years most children irrespective of socioeconomic setting will have been infected at least once. While infected, many children will be in need of medical attention due to extensive fluid loss.
Despite good access to effective antibiotics, Streptococcus pneumoniae (pneumococci) is still a major cause of disease and death in both developing and developed countries. Pneumococci are the main cause of bacterial respiratory tract infections, such as pneumonia, middle ear infection, and sinusitis, in all age groups.
Poliovirus is highly contagious and infected individuals shed virus in the faeces and from oral secretions, thus the mode of transmission is person-to-person, both via the faecal-oral and the oral-oral routes.
Haemophilus influenzae type b (Hib) is an obligate human pathogen and an important cause of invasive bacterial infections in both children and adults, with the highest incidence among young children.
Viral hepatitis is an inflammation of the liver caused by a virus. The most common hepatitis viruses in Europe are types A, B, and C (commonly referred to as HAV, HBV and HCV).
Hepatitis A is an acute infectious disease of the liver caused by the hepatitis A virus, a small, non-enveloped hepatotropic virus classified in the genus Hepatovirus within the family Picornaviridae.
Hepatitis B is a liver disease that results from infection with the hepatitis B virus (HBV) and is spread through contact with infected body fluids or blood products. Following acute infection with HBV, some people go on to develop a chronic infection.
Hepatitis E is an acute or chronic infection with the hepatitis E virus (HEV). In Europe, most of the infections are locally-acquired and asymptomatic.
Hepatitis C is a liver disease caused by infection with the hepatitis C virus (HCV). HCV can cause both acute and chronic hepatitis infection, ranging in severity from a mild illness that lasts only a few weeks to a serious, lifelong illness resulting in cirrhosis and liver cancer.