Despite good access to effective antibiotics, Streptococcus pneumoniae (pneumococci) is still a major cause of disease and death in both developing and developed countries. Pneumococci are the main cause of bacterial respiratory tract infections, such as pneumonia, middle ear infection, and sinusitis, in all age groups.
Smallpox was a systemic disease, officially eradicated since 1979 (WHO), caused by infection with the Variola major virus, whose only reservoir was infected humans.
Cryptosporidia are intestinal parasites infecting a variety of animals (e.g. cattle, sheep, rodents, cats and dogs, but also birds, fish and reptiles). Human infections occur due to Cryptosporidium parvum, a species that also affects domestic animals.
Despite good access to effective antibiotics, Streptococcus pneumoniae (pneumococci) is still a major cause of disease and death in both developing and developed countries.