Marburg virus disease (MVD), formerly known as Marburg haemorrhagic fever, is a severe disease in humans caused by Marburg marburgvirus (MARV). Although MVD is uncommon, MARV has the potential to cause epidemics with significant case fatality rates.
Smallpox was a systemic disease, officially eradicated since 1979 (WHO), caused by infection with the Variola major virus, whose only reservoir was infected humans.
HIV is a virus which attacks the immune system and causes a lifelong severe illness with a long incubation period. The end-stage of the infection, acquired immunodeficiency syndrome (AIDS), results from the destruction of the immune system.
Cryptosporidia are intestinal parasites infecting a variety of animals (e.g. cattle, sheep, rodents, cats and dogs, but also birds, fish and reptiles). Human infections occur due to Cryptosporidium parvum, a species that also affects domestic animals.
Dengue is a mosquito-borne viral disease widely spread in tropical and subtropical regions. It is transmitted by Aedes mosquitoes. Most of the clinical cases present a febrile illness, severe forms include hemorrhagic fevers and shock with fatalities.