Dengue fever virus particles, TEM. © Science Photo Library

Dengue is a mosquito-borne viral disease widely spread in tropical and subtropical regions. The disease is transmitted by Aedes mosquitoes, which breed in the peridomestic environment. While most of the clinical cases present a febrile illness, severe forms including hemorrhagic fevers and shock with fatalities are reported.

As dengue is a “viral hemorrhagic fever”, the disease is under European surveillance.  It is by far the most important mosquito-borne viral disease affecting humans worldwide; tens of millions of cases occur each year resulting in approximately 20,000-25,000 deaths mainly in children. 

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