This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 1-7 November 2025, and includes updates on respiratory virus epidemiology in the EU/EEA, SARS-CoV-2 variant classification, cholera, chikungunya, West Nile virus, dengue, Middle East respiratory syndrome (MERS), Cholera, Ebola, and Rift Valley Fever.
RSV and influenza activity remain at low levels in the EU/EEA; however, circulation of both viruses has begun to increase, with rises in the number of influenza virus infections occurring earlier than in recent seasons. COVID-19 activity, while still widespread, continues to decrease.
Since the beginning of 2025 and as of September 2025, over four million cases dengue cases and over 2 800 dengue-related deaths have been reported from 101 countries/territories in the WHO Region of Europe (EURO), the Regions of the Americas (PAHO), South-East Asia and West Pacific Regions (SEARO and WPRO, respectively), in the Eastern Mediterranean WHO Region (EMRO) and in Africa.
This report gives an overview of the countries and areas where dengue cases – and their corresponding case numbers - have been reported to the European surveillance portal for infectious diseases (EpiPulse).
ECDC plays an important role in supporting evidence-informed decision-making at both EU and national levels by providing data, analysis, risk assessments, operational guidance and public health advice.
This report provides an overview of current information on hepatitis B virus (HBV) vaccination among European Union (EU) and European Economic Area (EEA) countries.
The ECDC is marking its 20-year anniversary on a 4 November ceremony, bringing together representatives from the EU Institutions, Member States, international partners, and key stakeholders.