Pilot protocol for a COVID-19 vaccine effectiveness study using health data registries
This pilot protocol is primarily intended to guide the implementation of a first pilot ECDC-funded study using routinely collected data, and includes a concise overview of the systems of the countries included in the pilot study.
Postcard from the field: Deployment during the COVID-19 pandemic: Supporting vaccine effectiveness study implementation in the Republic of North Macedonia
Postcard from the field by Andreas Rohringer, EUPHEM cohort 2020.
COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines
EMA and ECDC have reviewed currently available studies and epidemiological data to provide a common position for EU/EEA countries on the current need and potential benefit of a fourth dose (second booster dose) of mRNA COVID-19 vaccines.
Interim analysis of COVID-19 vaccine effectiveness against Severe Acute Respiratory Infection due to laboratory-confirmed SARS-CoV-2 among individuals aged 30 years and older, ECDC multi-country study – second update
This second update contains vaccine effectiveness results among individuals aged 30 years and older, for the pre-Delta and the Delta-dominant periods (3 January–31 May 2021 and 1 July–15 December 2021, respectively).
COVID-19 vaccine effectiveness in adolescents aged 12–17 years and interim public health considerations for administration of a booster dose
The purpose of this document is to review the evidence of COVID-19 vaccine effectiveness and duration of immunity following vaccination in adolescents aged 12-17 years, and to outline interim public health considerations for the potential use of a booster dose in this group.
Systematic review of the efficacy, effectiveness and safety of high-dose seasonal influenza vaccines for the prevention of laboratory-confirmed influenza in individuals ≥18 years of age
Comber, L., Murchu, E.O., Jordan, K., Hawkshaw, S., Marshall, L., O'Neill, M., Teljeur, C., Ryan, M., Carnahan, A., Pérez Martín, J.J., Robertson, A.H., Johansen, K., de Jonge, J., Krause, T., Nicolay, N., Nohynek, H., Pavlopoulou, I., Pebody, R., Penttinen, P., Soler-Soneira, M., Wichmann, O., Harrington, P.
Systematic review of the efficacy, effectiveness and safety of recombinant haemagglutinin seasonal influenza vaccines for the prevention of laboratory-confirmed influenza in individuals ≥18 years of age
Murchu, E.O., Comber, L., Jordan, K., Hawkshaw, S., Marshall, L., O'Neill, M., Ryan, M., Teljeur, C., Carnahan, A., Pérez, J.J., Robertson, A.H., Johansen, K., Jonge, J., Krause, T., Nicolay, N., Nohynek, H., Pavlopoulou, I., Pebody, R., Penttinen, P., Soler-Soneira, M., Wichmann, O., Harrington, P.
Early influenza cases indicate the possibility of severe upcoming season for elderly
Although the overall number of influenza detections in the majority of EU/EEA countries is still low, indications show that influenza circulation is above the seasonal threshold in Croatia, which is unusually early. The main reported subtype among the cases recorded in EU/EEA during the past month is A(H3N2), which disproportionally affects older people, and is associated with lower vaccine effectiveness. This is a sign that the upcoming influenza season could be severe for elderly people, and that influenza patterns may vary between countries in terms of timing.
Flu Awareness Campaign 2021
The Flu Awareness Campaign is marked across the WHO European Region every year in October. It aims to raise awareness of the importance of vaccination for people’s health and well-being and to increase the uptake of seasonal influenza vaccination of people with underlying risk factors.
ECDC builds study infrastructure to monitor COVID-19 vaccine effectiveness
ECDC is creating new infrastructure to allow for regular monitoring and analysis of COVID-19 vaccine effectiveness (VE) over time, using a multi-country approach, through the implementation of studies in different settings.