Despite good access to effective antibiotics, Streptococcus pneumoniae (pneumococci) is still a major cause of disease and death in both developing and developed countries. Pneumococci are the main cause of bacterial respiratory tract infections, such as pneumonia, middle ear infection, and sinusitis, in all age groups.
Haemophilus influenzae type b (Hib) is an obligate human pathogen and an important cause of invasive bacterial infections in both children and adults, with the highest incidence among young children.
Yellow fever (YF) is a mosquito-borne infection, distributed in west, central and east Africa and in South America. The disease can cause a wide spectrum of symptoms, from mild to fatal. In severe cases there may be spontaneous haemorrhage. Mortality of these clinical cases can be as high as 80%, on a par with Ebola, Marburg and other haemorrhagic viral infections.
Haemophilus influenzae type b (Hib) is an obligate human pathogen and an important cause of invasive bacterial infections in both children and adults, with the highest incidence among young children.
The transmission of Clostridioides difficile can be patient-to-patient, via contaminated hands of healthcare workers or by environmental contamination.
Cholera is an acute diarrhoeal infection caused by the bacterium Vibrio cholera of serogroups O1 or O139. Humans are the only relevant reservoir, even though Vibrios can survive for a long time in coastal waters contaminated by human excreta.
Yellow fever (YF) cause a wide spectrum of symptoms, from mild to fatal. In severe cases there may be spontaneous haemorrhage. Mortality of these clinical cases can be as high as 80%, on a par with Ebola, Marburg and other haemorrhagic viral infections.
Diphtheria is spread through droplets from coughing or sneezing. Most often the disease causes a sore throat and low grade fever in the first few days of the illness.