Smallpox was a systemic disease, officially eradicated since 1979 (WHO), caused by infection with the Variola major virus, whose only reservoir was infected humans.
Cholera is an acute diarrhoeal infection caused by the bacterium Vibrio cholera of serogroups O1 or O139. Humans are the only relevant reservoir, even though Vibrios can survive for a long time in coastal waters contaminated by human excreta.
Severe acute respiratory syndrome (SARS) is a life-threatening respiratory disease caused by a recently identified coronavirus; the SARS-associated coronavirus (SARS-CoV). This is believed to be an animal virus that recently crossed the species barrier to infect humans.