Systematic review of the efficacy, effectiveness and safety of newer and enhanced seasonal influenza vaccines
Overall the evidence base for the efficacy and effectiveness of newer and enhanced influenza vaccines appears limited at present, with a number of potentially relevant studies identified as ongoing.
It is likely that the use of such vaccines provides greater protection than no vaccination at all, when the usual considerations of circulating strain matching are applied. Evidence regarding the comparability of these vaccines to traditional seasonal influenza vaccines is uncertain with a lack of available literature.
The safety profiles of these vaccines are largely in keeping with that expected when considering their individual compositions and, for the most part, they appear to be well tolerated.
Some suggestions are provided to enhance research conduct and reporting regarding these newer and enhanced influenza vaccines which are anticipated to improve the data coverage overall and facilitate future decision-making regarding the use of such vaccines.
Seasonal influenza is a preventable infectious disease with mostly respiratory symptoms. It is caused by influenza virus and is easily transmitted, predominantly via the droplet and contact routes and by indirect spread from respiratory secretions on hands etc.Read more
Immunisation and vaccines
Vaccines represent one of the most effective and cost-saving public health intervention.Read more
Influenza Virus Characterisation Reports, summary Europe
The influenza virus characterisation reports give an overview of circulating influenza viruses in Europe. They provide details on the current vaccine strains, summarise the development of the viruses since the last report, and closely follow the main developments for the ongoing influenza season.Read more