Despite good access to effective antibiotics, Streptococcus pneumoniae (pneumococci) is still a major cause of disease and death in both developing and developed countries.
Sindbis virus is widely and continuously found in insects, such as Culex mosquitoes, in Eurasia, Africa, and Oceania. However, clinical infection in humans has almost exclusively been reported in northern Europe where it is endemic and where large outbreaks occur intermittently.