Despite good access to effective antibiotics, Streptococcus pneumoniae (pneumococci) is still a major cause of disease and death in both developing and developed countries. Pneumococci are the main cause of bacterial respiratory tract infections, such as pneumonia, middle ear infection, and sinusitis, in all age groups.
Poliovirus is highly contagious and infected individuals shed virus in the faeces and from oral secretions, thus the mode of transmission is person-to-person, both via the faecal-oral and the oral-oral routes.
Hepatitis C is a liver disease caused by infection with the hepatitis C virus (HCV). HCV can cause both acute and chronic hepatitis infection, ranging in severity from a mild illness that lasts only a few weeks to a serious, lifelong illness resulting in cirrhosis and liver cancer.
The transmission of Clostridioides difficile can be patient-to-patient, via contaminated hands of healthcare workers or by environmental contamination.
Enteric infections due to Salmonella bacteria are generally referred to by the term ‘salmonellosis’ when they are due to Salmonella species other than Salmonella typhi and Salmonella paratyphi.
Cryptosporidia are intestinal parasites infecting a variety of animals (e.g. cattle, sheep, rodents, cats and dogs, but also birds, fish and reptiles). Human infections occur due to Cryptosporidium parvum, a species that also affects domestic animals.
Botulism is a serious paralytic illness caused by a nerve toxin produced by the bacterium Clostridium botulinum. The disease may occur after eating foods containing the toxin or due to development of the spores within the intestine of young children or within wounds.