Invasive pneumococcal disease - Annual Epidemiological Report for 2022
In 2022, 17 700 confirmed cases of invasive pneumococcal disease (IPD) were reported in the European Union/European Economic Area. The crude notification rate was 5.1 cases per 100 000 population, similar to 2018 and 2019. Age-specific rates were highest in infants under one year old (13.4 confirmed cases per 100 000 population) and in adults 65 years old and above (12.6 confirmed cases per 100 000 population), with higher rates reported in males than females among all age groups. The most common serotypes were 3, 8, 19A, 22F, 6C, 23B, 9N, 4, 23A 11A, and 15A (in order of decreasing frequency), accounting for 73.9% of typed isolates. Of cases under five years old for whom serotype information was available, approximately 46% were caused by a serotype included in the 13-valent pneumococcal conjugate vaccine (PCV13). This proportion has increased over the last five years. Among cases 65 years old and above, approximately 71% of cases with serotype information available were caused by serotypes included in the 23-valent polysaccharide
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