Monkeypox situation update, as of 22 November 2022

Epidemiological update

Since the last update on 8 November 2022, and as of 22 November 2022, 42 monkeypox (MPX) cases have been reported from 10 EU/EEA countries.

Updates on EU/EEA countries, the Western Balkans and Türkiye

Since the last update on 8 November 2022, and as of 22 November 2022, 42 monkeypox (MPX) cases have been reported from 10 EU/EEA countries. 

Excluding data from the last three weeks, which may be incomplete, 41 cases were reported in week 43 (24–30 October 2022), a decline of 19.6% compared to week 42 (17–23 October 2022).   

Compared to the peak of reported cases (2 163 cases during week 29; 18–24 July 2022), there has been a decrease of 98.1% in the number of newly reported cases during week 43. 

As of 22 November 2022, 15 countries have not reported an MPX case for more than 21 days.  

Since the start of the monkeypox outbreak and as of 22 November 2022, 20 887 confirmed cases of MPX have been reported from 29 EU/EEA countries, and 62 cases have been reported from three Western Balkan countries and Türkiye. 

Global update

According to the ‘2022 Monkeypox Outbreak: Global Trends’ report published by the World Health Organization (WHO), there is a decreasing trend in the number of new MPX cases reported globally, with a decrease of 3.7% in the number of reported cases in week 46 (14–20 November 2022) compared to week 45 (7–13 November 2022). According to the report, globally, the majority of cases (91.9%) were reported in the Region of the Americas. 

Risk assessment

Based on the updated ECDC risk assessment, and the declining number of new infections, the overall risk of MPX infection is assessed as moderate for men who have sex with men (MSM) and low for the broader population. 

MPX continues to primarily affect MSM between 18 and 50 years of age. Mass gatherings and specific sexual practices are likely to have facilitated the transmission of MPX among this group. 

The weekly number of MPX cases reported in the EU/EEA peaked in July 2022, and a steady declining trend has been observed since then. Multiple factors have probably contributed to the decline of this outbreak, including efforts in risk communication and community engagement, increasing immunity in the most affected population groups due to natural immunity and vaccination, and a decrease in the number of large cultural and social events frequented by the main risk groups for this outbreak after the summer. Options for EU/EEA countries to respond to MPX cases include raising awareness of health professionals, supporting sexual health services to continue case detection, contact tracing, and management of cases; continuing to offer testing for orthopoxvirus; a vaccination strategy; and continuing risk communication and community engagement, despite the decreasing number of cases.  

ECDC is closely monitoring the MPX epidemiological situation and will review the level of risk according to the evolution of the outbreak.   

Note: Data presented in this update are compiled from TESSy. 

More surveillance reports

Number of confirmed monkeypox cases reported weekly in the EU/EEA, Western Balkans and Türkiye, as of 22 November 2022

Number of confirmed monkeypox cases reported weekly in the EU/EEA, Western Balkans and Türkiye, as of 22 November 2022
Data should be interpreted with caution due to notification delays. Please note that the data for recent weeks may be incomplete.

Number and proportion of monkeypox cases reported weekly by global WHO regions, as of 22 November 2022

Number and proportion of monkeypox cases reported weekly by global WHO regions, as of 22 November 2022