Since the previous update on 22 August 2025 and as of 27 September 2025, there have been 21 266 chikungunya virus disease (CHIKVD) cases, including 10 associated deaths reported worldwide from seven countries, of which two are EU/EEA countries.
This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 1-7 November 2025, and includes updates on respiratory virus epidemiology in the EU/EEA, SARS-CoV-2 variant classification, cholera, chikungunya, West Nile virus, dengue, Middle East respiratory syndrome (MERS), Cholera, Ebola, and Rift Valley Fever.
RSV and influenza activity remain at low levels in the EU/EEA; however, circulation of both viruses has begun to increase, with rises in the number of influenza virus infections occurring earlier than in recent seasons. COVID-19 activity, while still widespread, continues to decrease.
Since the beginning of 2025 and as of September 2025, over four million cases dengue cases and over 2 800 dengue-related deaths have been reported from 101 countries/territories in the WHO Region of Europe (EURO), the Regions of the Americas (PAHO), South-East Asia and West Pacific Regions (SEARO and WPRO, respectively), in the Eastern Mediterranean WHO Region (EMRO) and in Africa.
This report gives an overview of the countries and areas where dengue cases – and their corresponding case numbers - have been reported to the European surveillance portal for infectious diseases (EpiPulse).
ECDC plays an important role in supporting evidence-informed decision-making at both EU and national levels by providing data, analysis, risk assessments, operational guidance and public health advice.