Diphtheria - Annual Epidemiological Report for 2024

Surveillance and monitoring

In 2024, 151 cases of diphtheria were reported to ECDC: 83 cases due to toxigenic Corynebacterium diphtheriae and 65 cases due to Corynebacterium ulcerans.

  • The increase in cases of diphtheria among migrants, reported in several EU/EEA countries during the second half of 2022, is continuing to decline.
  • C. diphtheriae cases were reported among all age groups, with 74% of cases in males. C. ulcerans cases were more common in adults aged 65 years and above, with 58% of cases in males.
  • Among the C. diphtheriae cases with importation status available, 21% were reported as imported (having been outside the country of notification during the incubation period, with no links to local transmission), and 57% of the imported cases presented with a cutaneous infection.
  • Vaccination status was available for 43% of all cases. Sixty-two percent of the cases with known vaccination status were unvaccinated, or vaccinated with an unknown number of doses.
  • Vaccination with the diphtheria toxoid vaccine is the only effective method for preventing this toxin-mediated disease. Achieving and sustaining high vaccination coverage in the population is critical to prevent toxigenic diphtheria from causing serious or fatal illness.
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Diphtheria - Annual Epidemiological Report for 2024

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