Protocol for genomic surveillance of carbapenem-resistant Enterobacterales 2025 (CRE25 survey)

The primary EU-level public health objective of the CRE25 survey is to determine the occurrence, geographical distribution and population dynamics of high-risk CRE lineages and related transmissible genetic elements of critical public health importance within healthcare settings in Europe, to inform risk assessment and control policies. A secondary objective is to support participating countries in developing technical capability and proficiency for genomic-based surveillance and for conducting risk assessments of multidrug-resistant pathogens with epidemic potential.