Dengue worldwide overview

In Madeira, two locally acquired cases were reported on 18 February, with symptom onset in January 2025. In the third week of January, entomological investigations confirmed the presence of dengue in mosquitoes captured on Madeira.

In Guadeloupe, the circulation of the virus continues within the archipelago, being classified epidemic of phase 2 level 1 (isolated outbreaks) (Dengue Epidemiological Bulletin of French Antilles, 3 October 2025). On 12 December 2025, the regional bulletin reports that the circulation of dengue has intensified in Martinique and that in Guadeloupe the indicators are at expected levels (inter-epidemic period) (Dengue Epidemiological Bulletin of French Antilles, 11 December 2025). As of October, in Saint Martin and Saint Barthelemy dengue circulation continued, but at lower levels (epidemic phase 1) (Dengue Epidemiological Bulletin of French Antilles, 3 October 2025). On 12 December, it was reported that the circulation remained at low levels (Dengue Epidemiological Bulletin of French Antilles, 11 December 2025). 

In French Guiana, 299 cases had been reported until 16 November 2025 and the following four weeks (period 17 November-7 December) dengue activity continued to be low with a total of ten confirmed cases (Health surveillance in French Guiana. Bulletin of December 11, 2025, Health surveillance in French Guiana. Bulletin of 20 November 2025, Health surveillance in French Guiana. Bulletin of December 4, 2025). Over 90% of the serotyped samples are DENV-2 (Health surveillance in French Guiana. Bulletin of 20 November 2025.). In Mayotte, 30 dengue cases have been reported this year as 8 September 2025. No cases of dengue have been detected in recent weeks (Health surveillance in Mayotte. Bulletin of 14 November 2025.). In Réunion , 44 dengue cases, of which 17 confirmed, have been reported since the beginning of the year (Health surveillance in Reunion Island. Bulletin of 14 August 2025). The last autochthonous case was identified in week 17 of 2025 (end of April) (Surveillance sanitaire à La Réunion. Bulletin du 6 novembre 2025, Surveillance sanitaire à La Réunion. Bulletin du 12 décembre 2025). 

A summary of recent epidemiological trends of dengue outside EU/EEA is presented below. The summary is based on available information from official sources and reports from different countries/territories. 

The Americas

In the PAHO, as of week 46 of 2025 (ending 16 November 2025), over 4.2 million cases have been reported of which 38% are laboratory confirmed. Cases peaked in weeks 12-14 2025 and a decreasing and plateauing trend was observed afterwards. The currently reported cases are 67% less compared to the cases reported in the same period in 2024 and 9% above the average of the last five years, according to the WHO PAHO report published on 5 December 2025. While all serotypes have been reported as of week 46 of 2025, their distribution differs in the different countries of PAHO (Report on the epidemiological situation of dengue in the Americas). 

Asia

According to the SEARO report published on 3 December 2025, a decreasing trend in the number of cases is being reported in Bangladesh following an increase since August continues (total 4 128 new cases reported the week 24-30 November 2025 compared to 5 267 cases reported the week 17-23 November). 

The total number of cases reported to date in 2025 is slightly higher than the total reported the same period in 2024 (95 081 cases reported in 2025 as of week 48 ending 30 November 2025 versus 92 351 cases reported in 2024 until week 48). 

• India continues reporting cases of dengue, too, showing an increasing trend since June 2025 and until October 2025. A total 91 015 cases have been reported until October 2025 which is overall lower than cases reported in the same period in 2024 (184 712 cases until October 2024).
• Cases of dengue have also been reported in 2025 by Thailand (with a total 51 795 cases reported this year until 31 October 2025, a plateau noted since September after the peak of July 2025),
• Sri Lanka (45 422 cases in 2025 until week 16-23 November), and
• Nepal (6 967 cases in 2025 until October; overall, lower than the cases reported the same period the last two years but increasing trend in the monthly number of cases).
• No updates are provided about Maldives since September 2025 when 254 cases were reported and an overall increasing trend in the monthly number of cases had been noted since June 2025.

According to the WPRO Dengue Situation update of 27 November 2025, in 2025, in Indonesia, Malaysia, Laos, and Singapore the number of dengue cases are lower than those reported in 2024: 

• Indonesia: 122 110 cases as of September 2025;
• Malaysia: 48 766 cases reported as of 15 November 2025;
• Laos: 11 261 cases and one death as 16 November 2025;
• Singapore: 3 776 cases in 2025 and as of 15 November).
• In Viet Nam cases continue showing an increasing trend the last weeks with a cumulative of 156 828 cases and 32 deaths as of 20 November 2025.
• In China, the monthly number of cases reported in October was 3 727 compared to 2 321 cases that were reported in September. Overall in 2025 and as of end of October 9 007 cases have been reported which is lower than the number of cases in the same period in 2024. 

Africa

Since the beginning of 2025, in Africa, over 58 000 cases and 100 deaths had been reported from:

• Burkina Faso,
• Cabo Verde,
• Comoros,
• Guinea,
• Kenya,
• Mali,
• Mauritania,
• Mauritius,
• Nigeria,
• Senegal, and
• Sudan. 

Overall, according to Africa CDC, less countries in Africa have reported dengue in 2025 compared to 2024 (11 countries in 2025 vs 15 countries in 2024) until early December. Moreover, the total number of cases is lower compared to the total number of cases reported in the same period in 2024 when over 150 000 cases had been reported (Africa CDC Epidemic Intelligence Weekly Report, December 2024 – Africa CDC). Most cases reported in 2024 were from Burkina Faso (over 100 000 cases). Burkina Faso has reported less than 1 000 cases in 2025. Africa CDC Epidemic Intelligence Weekly Report, December 2025 – Africa CDC).