The current status of invasive pneumococcal disease in PolandArchived
This study assesses the incidence of IPD (2006–2009), the serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae isolates.
Skoczynskaa A, Sadowyc E, Bojarskab K, Strzelecki J, Kucha A, Gołebiewskaa A, Waskoa I, Forys M, van der Lindend M, Hryniewicza W and Participants of a laboratory-based surveillance of community acquired invasive bacterial infections (BINet). Vaccine 2011; 29: 2199–2205
Mass vaccination against invasive pneumococcal disease (IPD) has not yet been implemented in Poland. This study assesses the incidence of IPD (2006–2009), the serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae isolates. The IPD incidence rates were highest among children under 2 years of age (3.39/100,000 in 2009) and children 2–5 years old (2.44/100,000). The most common serotypes were 14, 3, 1, 4, 19F, 23F, 6B, and 12F (61.7% of all isolates). In children aged less than 5 years, isolates of serotypes 14, 6B, and 19F were most prevalent (52.7% of the IPD cases). The PCV7, PCV10, and PCV13 covered 43.3%, 54.8%, and 68.8% of all IPD cases, and 68.7%, 76.3%, and 86.3% of cases involving children under 5 years of age. Penicillin resistance was found in 21.3% of the isolates responsible for meningitis and in 1.2% of isolates responsible for other invasive infections.The authors conclude that the introduction of antipneumococcal conjugated vaccines into the national immunisation programme would likely lead to a significant reduction of IPD-associated morbidity among Polish children in particular, as well as in the population as a whole, especially in cases involving pneumococci with a decreased susceptibility to antibiotics.
Decline in early childhood respiratory tract infections in the norwegian mother and child cohort study after introduction of pneumococcal conjugate vaccinationArchived
27 Nov 2012 - The study design and analysis controlled for influence of potentially confounding trends, such as improvement of day-care carriage and decreasing prevalence of smoking during the study period.
A review of the effect of immunization programs on antimicrobial utilizationArchived
16 Oct 2012 - Antimicrobial stewardship policies are increasingly being implemented as a measure to prevent and control antimicrobial resistance.
Four years of universal pneumococcal conjugate infant vaccination in Germany: Impact on incidence of invasive pneumococcal disease and serotype distribution in childrenArchived
16 Aug 2012 - The study compares the incidence and serotype distribution of invasive pneumococcal disease (IPD) for pneumococcal meningitis and non-meningitis IPD in children from 2007 to 2010 with reference to the pre-vaccination period from 1997 to 2001 in Germany.