Hospices Civils de Lyon - EUPHEM

acknowledged by EUPHEM
Laboratoire de Virologie, IAI, Groupement Hospitalier NORD
FR-69317 LYON cedex 04,

Contact person

Bruno Lina

Tel: +33 472 07 10 20 / +33 472 07 10 57

Description of the institute

The Hospices Civils de Lyon is the Public Hospital in Lyon. This multi-site hospital has about 6 000 beds, is a referral hospital for a very large panel of infectious diseases including those caused by BSL-4 agents. The core of laboratories involved in the training have public health mandates for the surveillance of several specific pathogens in link with the Institut de Veille Sanitaire and the WHO.

The hospital has very strong links with research teams headed by the co-supervisors of this proposal. The hospital-based structure of the laboratory network allows the rapid identification of public health infectious diseases, and the possibility for real-time intervention if needed.

The human and technical resources available in the labs will provide full access to state of the art technology to undertake molecular and genetic studies, such as next generation sequencing with a specialist bioinformatics and mathematical modelling department for interpretation of specialised molecular sequence to perform epidemiological surveillance, studies on pathogenesis and pathogen evolution or on antimicrobial resistance. In addition, new epidemiological tools are available for the measurement of contact between health care workers.

Four National reference microbiology laboratories are within the frame of the offered package for this training site, inclusive all of state of the art technology for strain characterisation and microbial epidemiology in support of outbreak investigations and surveillance programmes.

  • The main public health programmes are:
    • Respiratory infections
    • Gastrointestinal and foodborne infections
    • Healthcare associated infections
    • Nosocomial infections
    • Parasitic diseases
    • Vaccine preventable diseases
    • Antimicrobial resistance (Bacteria, Parasites and Viruses)


  • The main public health core-functions are:
    • Microbiological Surveillance of vaccine preventable diseases
    • Investigation and control of communicable disease.
    • Investigation of nosocomial infection
    • Research activities in link with public health microbiology
    • Surveillance for specific diseases (in link with the National Reference Centres)


Training opportunities

Bruno LINA and Prof Florence MORFIN
Institut des agents Infectieux, Laboratoire de Virologie Nord (Clinical lab)
Nat ref centre for Influenza, WHO National Influenza Centre, Nat ref centre for Enterovirus and Parechovirus, WHO National Polio Lab.
The training will include work in a BSL-3 lab

Prof Francois VANDENESCH, Prof Gérard LINA, Prof Frederic LAURENT
Institut de Microbiologie, laboratoire de Bactériologie (Clinical lab)
Nat ref centre for Staphylococcal diseases, Nat ref centre for Legionella, Ref lab for Mycobacteria
The training will include work in a BSL-3 lab

Prof Stephane PICOT, Prof Martine WALLON
Laboratoire de Parasitologie

Prof Philippe VANHEMS
Unité Hygiène, Epidémiologie et Prévention,
Corevac Vaccine research program

Training supervision
Supervisor :Bruno Lina
Laboratoire de Virologie Nord, Institut des agents Infectieux, CBPN, GHN, 103 grande rue de la Croix-Rousse, 69371 Lyon cedex 04
Tel +33 472 07 10 20

Co-supervisor: Prof Philippe VANHEMS
Unité Hygiéne, Epidémiologie et Prévention, Hopital Edouard Herriot, 5, place d’Arsonval, 69437 LYON cedex 03
Tel +33 472 11 07 21

Language requirements

English required,



Training history

  • Number of EUPHEM fellows trained at institute: 1
  • EUPHEM fellow trained in 2011-2013 (Cohort 2)