Dengue worldwide overview

In Madeira, two locally acquired cases were reported on 18 February, with symptom onset in January 2025. In the third week of January, entomological investigations confirmed the presence of dengue in mosquitoes captured on Madeira. 

In Guadeloupe, the circulation of the virus continues to within the archipelago, being classified epidemic of phase 2 level 1 (isolated outbreaks) (Dengue Epidemiological Bulletin of French Antilles, 3 October 2025). The most prevalent serotype continues to be DENV-3. In Martinique, the epidemiological situation is characterised as phase 1 (sporadic cases reported). In Saint Martin and Saint Barthelemy dengue circulation continues, but at lower levels (epidemic phase 1) (Dengue Epidemiological Bulletin of French Antilles, 3 October 2025). In Guyane, dengue activity continued to be low with a total of nine confirmed cases in weeks 44 and 43. Since the beginning of the year, 293 dengue cases have been confirmed and 97% of the 195 serotyped samples are DENV-2 (Surveillance sanitaire en Guyane. Bulletin du 6 novembre 2025). In Mayotte, 30 dengue cases have been reported this year as 8 September 2025. No cases of dengue have been detected in recent weeks (Surveillance sanitaire à Mayotte. Bulletin du 13 octubre 2025). In Reunion, 44 dengue cases, of which 17 confirmed, have been reported since the beginning of the year (Health surveillance in Reunion Island. Bulletin of 14 August 2025). The last autochthonous case was identified in week 17 of 2025 (end of April) (Surveillance sanitaire à La Réunion. Bulletin du 6 novembre 2025). 

A summary of recent epidemiological trends of dengue outside EU/EEA of the first seven months of 2025 is presented below. The summary is based on available information from official sources and reports from different countries/territories. 

In the PAHO, as of week 40 of 2025, over 3.9 million cases have been reported of which 40% are laboratory confirmed. Cases peaked in weeks 12-14 2025 and a decreasing trend was observed afterwards. The currently reported cases are 68% less compared to the cases reported in the same period in 2024 and 9% above the average of the last five years, according to the WHO PAHO report published on 27 October 2025. While all serotypes have been reported as of week 40 of 2025, their distribution differs in the different countries of PAHO (Report on the epidemiological situation of dengue in the Americas). 

According to the SEARO report published on 5 November 2025, the increasing trends in the number of cases reported in Bangladesh since August continues (total 6 235 new cases reported the week 27 October - 2 November 2025 compared to 5 591 cases reported the week of 20-26 October). The total number of cases reported so far in 2025 is higher than the total reported the same period in 2024. India continues reporting cases of dengue, too. A decreasing trend is noted in Kerala and Karnataka. In both areas, the cases are lower compared to the same period last year, as reported also in September 2025. Cases of dengue have also been reported in 2025 by Thailand (continuous decreasing trend since peak in July with a total 47 981 cases reported this year until 30 September 2025), Sri Lanka (41 946 cases in 2025 until week 20-26 October), Maldives (254 cases reported in September 2025; there is an overall increasing trend in the monthly number of cases that has not peaked in 2025) and Nepal (5 323 cases in 2025; overall, lower than the cases reported the same period the last two years but increasing trend in the monthly number of cases). 

According to the WPRO Dengue Situation update of 30 October 2025, in 2025, in Indonesia, Malaysia, Laos, and Singapore dengue cases are lower than those reported in 2024 (Indonesia: 118 021 cases as of August 2025; Malaysia: 44 382 cases reported as of 11 October 2025, Laos: 10 204 cases and one death as 19 October 2025; Singapore: 3 5932 cases in 2025 and as of 18 October). In Viet Nam cases continue showing an increasing trend the last weeks with a cumulative of 122 979 cases and 23 deaths as of 17 October 2025. In China, the monthly number of cases reported in September was 2 321 compared to 1 702 cases that were reported in August 2025. Overall in 2025 and as of end of September 5 280 cases have been reported which is lower than the number of cases in the same period in 2024. 

In Afghanistan (according to WHO EMRO), in 2025, the number of suspected dengue fever cases shows an increase since week 15 of 2025 (mid-April), with 1 737 cases reported as of September 2025 (Afghanistan Emergency Situation Report September 2025). 

Since the beginning of 2025, in Africa, over 40 000 cases and 100 deaths had been reported from Burkina Faso, Cabo Verde, Comoros, Guinea, Kenya, Mali, Mauritius, Nigeria, Senegal and Sudan. In week 43 cases were reported by Mali, Mauritania and Sudan according to Africa CDC (Africa CDC Epidemic Intelligence Weekly Report, November 2025 – Africa CDC).