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  • Remove this filter Public health area: Immunisation
  • Infectious disease
    • Vaccine preventable diseases (22)
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Oct 2015

Event

Understanding the association between narcolepsy and one of the 2009 adjuvanted influenza A (H1N1) vaccines

Event
23 Oct 2015
Geneva, Switzerland
International Alliance for Biological Standardisation and the World Health Organization

​This meeting was designed to offer a place to exchange the latest information on into the development of narcolepsy following vaccination with one of the 2009 adjuvanted influenza A(H1N1) vaccines.

  • EU/EEA
  • Immunisation
  • Influenza
  • Influenza A (H1N1)2009
  • Influenza in humans, pandemic
  • Influenza in humans, seasonal
  • Vaccine safety

News

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2

ECDC comment - 3 Jul 2015

This new publication from Novartis in collaboration with public health and academic researchers in Finland and the US adds to the evidence-base on how narcolepsy might have been triggered in genetically susceptible individuals.

  • Immunisation
  • Influenza
  • Influenza in humans, seasonal
  • Vaccine safety

News

Update on narcolepsy cases associated with Pandemrix vaccination in 2009 in the Netherlands

ECDC comment - 22 Dec 2014

​In November 2014, the Pharmacovigilance Centre of Netherlands (Lareb) provided an updated overview of Dutch cases of narcolepsy reported to have a link to Pandemrix.

  • Immunisation
  • Influenza A (H1N1)2009
  • Influenza in humans, pandemic
  • Influenza in humans, seasonal
  • Vaccine safety

News

No Serological Evidence of Influenza A H1N1pdm09 Virus Infection as a Contributing Factor in Childhood Narcolepsy after Pandemrix™ Vaccination Campaign in Finland

ECDC comment - 15 Aug 2013

This is the first published study where an attempt has been made to understand the possible biological mechanisms behind development of narcolepsy following vaccination with Pandemrix™.

  • Finland
  • Immunisation
  • Influenza
  • Influenza A (H1N1)2009
  • Influenza in humans, pandemic
  • Influenza in humans, seasonal
  • Vaccine safety

News

New Swedish Registry study confirms increased risk of narcolepsy in children and adolescents after vaccination with Pandemrix

ECDC comment - 3 May 2013

This observational cohort study utilizing electronic health care records covering 5.8 million Swedes confirmed an increased risk of narcolepsy after vaccination with Pandemrix in children and adolescents (<

  • Immunisation
  • Influenza
  • Influenza A (H1N1)2009
  • Influenza in humans, seasonal
  • Vaccine safety

News

Association of receipt of Pandemrix™ and narcolepsy in children and adolescents in the UK (England)

ECDC comment - 18 Mar 2013

This is the sixth EU Member State reporting an association between the development of narcolepsy and vaccination with the AS03-adjuvanted influenza A H1N1 (2009) pandemic vaccine Pandemrix.

  • Immunisation
  • Influenza
  • Influenza A (H1N1)2009
  • Influenza in humans, seasonal
  • Vaccine safety

News

Narcolepsy and Pandemrix Vaccine – an association in adults as well as childrenArchived

ECDC comment - 24 Sep 2012

​In September 2010 Sweden and Finland noted a number of children had developed narcolepsy seemingly in association with having received the pandemic vaccine used almost exclusively in those countries (Pandemrix)

  • Finland
  • Immunisation
  • Influenza
  • Influenza A (H1N1)2009
  • Influenza in humans, seasonal
  • Sweden
  • Vaccine safety

News

Report on the association between the 2009 pandemic vaccine (Pandemrix®) and narcolepsy – Republic of IrelandArchived

ECDC comment - 19 Apr 2012

Investigation of an increase in the incidence of narcolepsy in children and adolescents in 2009 and 2010 - Final Report of National Narcolepsy Study Steering Committee, Department of Health, Ireland

  • Immunisation
  • Influenza
  • Influenza A (H1N1)2009
  • Influenza in humans, pandemic
  • Influenza in humans, seasonal
  • Ireland
  • Vaccine safety

News

Association of childhood narcolepsy and cataplexy and receipt of a pandemic influenza vaccine in Finland in 2009-10 – First papers in a peer review journalArchived

ECDC comment - 30 Mar 2012

​A pair of linked papers from Finland concerning the above topic, one epidemiological and the second combining both clinical and epidemiological were published on March 28th in the open access journal, PLoS One.(1,2).

  • Finland
  • Immunisation
  • Influenza
  • Influenza A (H1N1)2009
  • Influenza in humans, seasonal
  • Vaccine safety
Feb 2012

Event

Training workshop on vaccine safety for Member States, building on the experience obtained in the ECDC vaccine safety project VAESCOArchived

Event
23 Feb 2012 - 24 Feb 2012
Stockholm, Sweden
ECDC

ECDC organised a workshop aimed at the Member States not participating in the ECDC Vaccine safety network.

  • Immunisation
  • Influenza
  • Influenza A (H1N1)2009
  • Influenza in humans, seasonal
  • Vaccine safety

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