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This document provides guidance on diagnostic testing, molecular characterisation and metagenomic analysis for suspect cases of severe acute hepatitis of unknown aetiology.

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 15-21 May 2022 and includes updates on COVID-19, the arrival of people displaced from Ukraine to the EU following Russia's invasion of Ukraine, Influenza, polio virus, hepatitis, avian influenza, swine influenza, and poliomyelitis.

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 8-14 May 2022 and includes updates on COVID-19, Influenza, the arrival of people displaced from Ukraine to the EU following Russia's invasion of Ukraine, hepatitis, measles and monkeypox.

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 1-7 May 2022 and includes updates on COVID-19, Influenza, the arrival of people displaced from Ukraine to the EU following Russia's invasion of Ukraine, hepatitis, Ebola, Middle East respiratory syndrome coronavirus, chikungunya and dengue.

This reporting protocol is intended for reporting national case-based data for surveillance of hepatitis of unknown origin from all the countries and areas of the WHO European Region, including the 27 countries of the European Union (EU) and the additional three countries of the European Economic Area (EEA), to the European level.

An increase in severe acute hepatitis cases of unknown aetiology among previously healthy children was first reported by the United Kingdom (UK) on 5 April 2022.

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 17-23 April 2022 and includes updates on COVID-19, Influenza, the arrival of people displaced from Ukraine to the EU following Russia's invasion of Ukraine, hepatitis and poliomyelitis.

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 10-16 April 2022 and includes updates on COVID-19, the influx of people displaced from Ukraine to the EU following Russia's invasion of Ukraine, measles and hepatitis.

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 3-9 April 2022 and includes updates on COVID-19, the influx of people displaced from Ukraine to the EU following Russia's invasion of Ukraine, seasonal influenza, hepatitis, monophasic Salmonella Typhimurium, MERS-CoV, chikungunya and dengue.

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 6-11 March 2022, and includes updates on COVID-19, rat hepatitis E, seasonal influenza, measles, Japanese encephalitis, polio, MERS-CoV, dengue, chikungunya and the influx of people displaced from Ukraine to the EU following Russia's invasion of Ukraine.