Ebola treatment trial: two drugs identified as more effective
Two out of the four drugs tested in a multi-drug randomised control trial have been found more effective in treating Ebola, the World Health Organization announced on Monday. The Data and Safety Monitoring Board, an independent body that has been reviewing interim safety and efficacy data, has therefore recommended that the study be stopped and that all future patients be randomized to receive either REGN-EB3 or mAb114, in what is being considered an extension phase of the study.
The use of evidence in decision making during public health emergencies
This report is based upon a workshop (expert consultation) on 5–6 December 2018. The workshop sought to identify and address the links between scientific evidence and decision-making in public health
emergencies, and to address the key challenges faced by public health experts when advising decision makers.
Targeted testing for viral hepatitis: Europe’s persistent public health challenge
Targeted testing is an essential element of any strategy to eliminate viral hepatitis across the countries in the European Union and European Economic Area. Some preliminary monitoring results on the response to hepatitis B and C presented around World Hepatitis Day show that diagnosing chronic infections is still a challenge in the EU/EEA.
Syphilis and congenital syphilis in Europe - A review of epidemiological trends (2007–2018) and options for response
Since 2010, syphilis notification rates in the EU/EAA have been on the increase, but in recent years this trend seems to accelerate, predominantly among men having sex with men. Similar trends have been observed in high-income countries outside the EU/EAA. While the overall trend remained relatively stable, outbreaks or clusters of syphilis cases have also been reported among heterosexual populations in the EU/EEA. In several high-income countries (e.g. USA, Japan), increases in congenital syphilis occurred in connection with increases in syphilis notifications among women.
Syphilis notifications in the EU/EEA up by 70% since 2010
The number of syphilis cases has been consistently going up across Europe since 2010, mostly affecting men who have sex with men living in urban areas. In 2017, notification rates reached an all-time high in the EU/EEA countries with more than 33 000 reported cases. An in-depth ECDC study published today describes the factors behind this increase and outlines the evidence-based options for public health control of syphilis, including case finding and management as well as educational activities.
Isoniazid (INH) mono-resistance and tuberculosis (TB) treatment success: Analysis of European surveillance data, 2002 to 2014
Karo, B., Kohlenberg, A., Hollo, V., Duarte, R., Fiebig, L., Jackson, S., Kearns, C., Ködmön, C., Korzeniewska-Kosela, M., Papaventsis, D., Solovic, I., van Soolingen, D., van der Werf, M.J.
ECDC Expert consultation on community engagement in public health emergency preparedness
The expert consultation meeting organised by ECDC seeks to identify enabling factors and barriers to good practice in community engagement in the context of public health emergency preparedness. Outcomes of this meeting will inform the development of an ECDC guidance on the topic.
ECDC’s HEPSA preparedness self-assessment tool is now available in all EU/EEA languages
The HEPSA (Health Emergency Preparedness Self-Assessment) tool that ECDC launched in 2018 in English is now available in all EU/EEA languages. This tool aims at supporting countries in improving their level of public health emergency preparedness.
Laboratory management of Crimean-Congo haemorrhagic fever virus infections: Perspectives from two European networks
Bartolini, B., Gruber, C.E.M., Koopmans, M., Avšič, T., Bino, S., Christova, I., Grunow, R., Hewson, R., Korukluoglu, G., Lemos, C.M., Mirazimi, A., Papa, A., Sanchez-Seco, M.P., Sauer, A.V., Zeller, H., Nisii, C., Capobianchi, M.R., Ippolito, G., Reusken, C.B., Di Caro, A.