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This technical guidance aims to provide guidelines to laboratories and relevant stakeholders in the European Union (EU), European Economic Area (EEA) and other countries in the WHO European region in making decisions on establishing sequencing capacities and capabilities, in making decisions on which technologies to use and/or in deciding on the role of sequencing for SARS-CoV-2 diagnostics, research, outbreak investigations and surveillance.

This document outlines operational considerations for how to support the continuity of national influenza surveillance systems and public health laboratories for the epidemiological and virological surveillance for influenza in the 2020–2021 season during the ongoing COVID-19 pandemic.

European surveillance data show on-going transmission of viral hepatitis across the European Union and European Economic Area (EU/EEA). The available notification data however, do not provide a clear epidemiological picture of hepatitis C in Europe. Prevalence data from population surveys are a key source of information to complement the surveillance data for hepatitis C due to the limitations of surveillance for hepatitis: the infection is often asymptomatic and notifications are strongly influenced by local testing practices. The overarching aim of this toolkit is to gain a better understanding of the HCV epidemiology in the EU/EEA.

ECDC publishes a protocol developed for the surveillance of Clostridioides (Clostridium) difficile infections (CDI) to address the lack of standardised surveillance of CDI in EU Member States.

This report addresses the heterogeneity that arises from pooling data from different surveillance systems and provides statistical and procedural approaches to minimise or remove its impact. The aim is to support public health specialists and researchers in answering key research and policy questions using available European data to the fullest possible extent.

This operational guidance, developed by ECDC in collaboration with its hepatitis E virus (HEV) expert group, offers options on the implementation or adjustment of HEV surveillance at a national level.

This ECDC study protocol describes the technical requirements for implementing future EU-level genomic-based surveillance of carbapenem-resistant and/or colistin-resistant Enterobacteriaceae.

This document provides guidance to support epidemiologists and surveillance experts in producing tables, graphs and maps to show the results of their data analyses following harmonised principles and practices.

This protocol is to ensure standardisation of definitions, data collection and reporting procedures for hospitals participating in the national/regional surveillance of healthcare-associated infections in intensive care units across Europe.

This updated protocol prescribes the methodology, and provides the data collection tools required to achieve the objectives of European surveillance of CDIs.