Serotype replacement in disease after pneumococcal vaccinationArchived
The heptavalent pneumococcal conjugate vaccine (PCV7) targets seven of the more than 92 pneumococcal serotypes. Concerns have been raised that non-vaccine serotypes (NVTs) could increase in prevalence and reduce the benefits of vaccination. Indeed, among asymptomatic carriers, the prevalence of NVTs has increased substantially, and consequently, there has been little or no net change in the bacterial carriage prevalence.
Mumps Complications and Effects of Mumps Vaccination, England and Wales, 2002–2006Archived
The authors analyzed data from hospital admissions and enhanced mumps surveillance to assess mumps complications during the largest mumps outbreak in England and Wales, 2004–2005, and their association with mumps vaccination. When compared with non-outbreak periods, the outbreak was associated with a clear increase in hospitalized patients with orchitis, meningitis and pancreatitis. Routine mumps surveillance and hospital data showed that 6.1% of mumps patients were hospitalized, 4.4% had orchitis, 0.35% meningitis and 0.33% pancreatitis.
Paediatric pneumococcal disease in Central EuropeArchived
The authors present an appraisal of the pneumococcal epidemiological situation in 11 Central European countries. Data are based on study findings presented at the 12th Central European Vaccine Advisory Group (CEVAG) meeting, held on 21–22 May 2010 in Sofia, Bulgaria, and a literature review of the PubMed database.
Difficulties in estimating early incidence of influenza infection in a pandemic – study with multiple approaches in Singapore and a review of other studiesArchived
This paper and review from a Singapore-based group compared results obtained for estimating rates of new infections during the 2009 pandemic. They derived rates from paired specimens from the same patient (serum cohort approach), cross-sectional serological surveys, rates of unconfirmed syndromic influenza-like-illness (ILI) obtained from primary care physicians in sentinel general practices, and combined clinical repos with laboratory confirmed samples.
Two evaluations of the response to the 2009 Pandemic in Spain: Surveillance and Vaccines and antiviralsArchived
Two official evaluations have been made by the national Ministry of Health of Spain of their country’s response to the 2009 influenza pandemic. The reviews focused on two particular topics - Surveillance and Vaccines and Antivirals.
New drug resistant form of tuberculosis reported in IndiaArchived
In a recent scientific article (Udwadia, F et al. Clin. Infect. Dis. 2011, Dec 21, Eprint) four cases of so-called total drug resistant tuberculosis (TB) were reported from India.