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This guidance, based on a systematic review of the literature and expert opinion, suggests that there is good evidence to ensure that some key components are considered for inclusion in national and sub-national public health programmes in countries in Europe.

This literature review was conducted as part of a project evaluating the effectiveness of antenatal screening for HIV, hepatitis B, syphilis and rubella susceptibility in EU/EEA Member States.

In order to collect evidence on effective types of antenatal screening intervention that are effective for population groups vulnerable to MTCT, a review of the existing published literature was performed.

This publication aims to support the strengthening of antenatal screening programmes for HIV, hepatitis B, syphilis and rubella susceptibility in the general population and in groups identified as vulnerable to mother-to-child-transmission in the EU/EEA.