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While there have been some early descriptive reports of school outbreaks, for example a number published in Eurosurveillance from France and the UK this study is unusual in combining modelling, social network theory and ‘shoe-leather epidemiology’. 

This paper serves as a gateway review of several field and epidemiological investigations conducted across the United States (US) which have been compiled as a special supplement in a January 2011 number of the Clinical Infectious Diseases journal.

No neutralising or cross-reacting antibodies were found in the sampled human population.