Risk assessment: The risk of variant Creutzfeldt-Jakob disease transmission via blood and plasma-derived medicinal products manufactured from donations obtained in the United Kingdom
ECDC assessed the risk to the EU/EEA of the presence and the possible transmission of prions, which have been linked to Creutzfeldt-Jakob disease, by blood and plasma-derived medicinal products (PDMPs) manufactured from donations obtained in the UK.
Laboratory standard operating procedure for detecting sporadic Creutzfeldt-Jakob disease using Real- Time Quaking-Induced Conversion (RT-QuIC) assay
This document provides laboratories with a single protocol for producing recombinant full-length hamster prion protein and using it to perform the Real-Time Quaking-Induced Conversion assay (RT-QuIC), which can distinguish sporadic Creutzfeldt-Jakob disease (sCJD) from variant Creutzfeldt-Jakob disease (vCJD).
Variant Creutzfeldt−Jakob disease - Annual Epidemiological Report for 2017
No cases of variant Creutzfeldt−Jakob disease (vCJD) were identified in the EU/EEA in 2017. The disease remains extremely rare. This is consistent with the current understanding of the underlying epidemiology of vCJD and with the positive impact of risk mitigation measures introduced in the EU in the late 1980s to remove potential infectious animal material from the human food chain.
Creutzfeldt−Jakob disease - Annual Epidemiological Report for 2016
Two cases of variant Creutzfeldt−Jakob disease (vCJD) were identified in the EU/EEA in 2016: one probable case from Italy and one confirmed case from the UK.
Variant Creutzfeldt−Jakob disease - Annual Epidemiological Report 2016 [2014 data]
No new confirmed cases of variant Creutzfeldt−Jakob disease (vCJD) were reported in 2014.
Diagnostic workshop on Real-time quaking-induced conversion (RT-QuIC) to enhance MS capacity to diagnose CJD
In order to enhance the understanding of the methodology and its consistent application, a training day on the analytical and clinical aspects of analysing cerebrospinal fluid (CSF) samples by RT-QuIC in the investigation of patents with suspected sporadic CJD (sCJD) was held at the National CJD Research &amp; Surveillance Unit (NCJDRSU).
Real time quaking-induced conversion analysis of cerebrospinal fluid (CSF RT QuIC) diagnostic technique for the investigation of sporadic CJD workshop
The National Creutzfeld-Jakob Disease (CJD) Research & Surveillance Unit of the University of Edinburgh organized two one-day information workshops on Real time quaking-induced conversion analysis of cerebrospinal fluid (CSF RT QuIC) diagnostic technique for the investigation of sporadic CJD