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Publication

Risk assessment: The risk of variant Creutzfeldt-Jakob disease transmission via blood and plasma-derived medicinal products manufactured from donations obtained in the United Kingdom

Risk assessment - 3 Aug 2021

ECDC assessed the risk to the EU/EEA of the presence and the possible transmission of prions, which have been linked to Creutzfeldt-Jakob disease, by blood and plasma-derived medicinal products (PDMPs) manufactured from donations obtained in the UK.

The risk of variant Creutzfeldt-Jakob disease transmission via blood and plasma-derived medicinal products manufactured from donations obtained in the United Kingdom - EN - [PDF-624.04 KB]
  • EU/EEA
  • United Kingdom
  • Variant Creutzfeldt-Jakob disease (vCJD)

Publication

Laboratory standard operating procedure for detecting sporadic Creutzfeldt-Jakob disease using Real- Time Quaking-Induced Conversion (RT-QuIC) assay

Technical report - 8 Feb 2021

This document provides laboratories with a single protocol for producing recombinant full-length hamster prion protein and using it to perform the Real-Time Quaking-Induced Conversion assay (RT-QuIC), which can distinguish sporadic Creutzfeldt-Jakob disease (sCJD) from variant Creutzfeldt-Jakob disease (vCJD).

Laboratory standard operating procedure for detecting sporadic Creutzfeldt-Jakob disease using Real- Time Quaking-Induced Conversion (RT-QuIC) assay - EN - [PDF-1.98 MB]
  • EU/EEA
  • Laboratories
  • Variant Creutzfeldt-Jakob disease (vCJD)

Publication

Variant Creutzfeldt−Jakob disease - Annual Epidemiological Report for 2017

Surveillance report - 18 Sep 2020

No cases of variant Creutzfeldt−Jakob disease (vCJD) were identified in the EU/EEA in 2017. The disease remains extremely rare. This is consistent with the current understanding of the underlying epidemiology of vCJD and with the positive impact of risk mitigation measures introduced in the EU in the late 1980s to remove potential infectious animal material from the human food chain.

Variant Creutzfeldt−Jakob disease - Annual Epidemiological Report for 2017 - EN - [PDF-352.25 KB]
  • EU/EEA
  • Surveillance
  • Variant Creutzfeldt-Jakob disease (vCJD)

Publication

Creutzfeldt−Jakob disease - Annual Epidemiological Report for 2016

Surveillance report - 14 Mar 2019

Two cases of variant Creutzfeldt−Jakob disease (vCJD) were identified in the EU/EEA in 2016: one probable case from Italy and one confirmed case from the UK.

Creutzfeldt−Jakob disease - Annual Epidemiological Report for 2016 - EN - [PDF-352.03 KB]
  • EU/EEA
  • Surveillance
  • Variant Creutzfeldt-Jakob disease (vCJD)

Publication

Variant Creutzfeldt−Jakob disease - Annual Epidemiological Report 2016 [2014 data]

Surveillance report - 30 Dec 2016

No new confirmed cases of variant Creutzfeldt−Jakob disease (vCJD) were reported in 2014.

Variant Creutzfeldt−Jakob disease - Annual Epidemiological Report 2016 - EN - [PDF-83.75 KB]
  • Surveillance
  • Variant Creutzfeldt-Jakob disease (vCJD)
Apr 2015

Event

Diagnostic workshop on Real-time quaking-induced conversion (RT-QuIC) to enhance MS capacity to diagnose CJD

Event
27 Apr 2015 - 28 Apr 2015
Edinburgh
NCJDRSU and ECDC

​In order to enhance the understanding of the methodology and its consistent application, a training day on the analytical and clinical aspects of analysing cerebrospinal fluid (CSF) samples by RT-QuIC in the investigation of patents with suspected sporadic CJD (sCJD) was held at the National CJD Research & Surveillance Unit (NCJDRSU).

  • Variant Creutzfeldt-Jakob disease (vCJD)
Sep 2015

Event

European CJD Surveillance Experts Meeting

Event
17 Sep 2015 - 18 Sep 2015
Budapest, Hungary
ECDC

​​The EuroCJD Surveillance network hosted its biennial expert meeting in Budapest.

  • Epidemiology
  • EU/EEA
  • Surveillance
  • Variant Creutzfeldt-Jakob disease (vCJD)
Mar 2014

Event

Real time quaking-induced conversion analysis of cerebrospinal fluid (CSF RT QuIC) diagnostic technique for the investigation of sporadic CJD workshop

Event
11 Mar 2014 - 12 Mar 2014
Edinburgh, United Kingdom
ECDC

​The National Creutzfeld-Jakob Disease (CJD) Research & Surveillance Unit of the University of Edinburgh organized two one-day information workshops on Real time quaking-induced conversion analysis of cerebrospinal fluid (CSF RT QuIC) diagnostic technique for the investigation of sporadic CJD

  • Microbiology
  • Variant Creutzfeldt-Jakob disease (vCJD)

Publication

EuroCJD network meeting 2013

Meeting report - 11 Jul 2013
Annual-EuroCJD-network-meeting-2013.pdf - EN - [PDF-153.18 KB]
  • Surveillance
  • Variant Creutzfeldt-Jakob disease (vCJD)
Jun 2013

Event

Annual EuroCJD network meeting 2013

Event
6 Jun 2013 - 7 Jun 2013
Oslo, Norway
ECDC

The EuroCJD meetings are held annually/biannually and constitute a valuable platform for: 1) the assessment of the latest scientific and diagnostic findings and developments in the field of CJD; 2) the assessment of their impact on the needs of future surveillance; and 3) sharing country-specific experience, case studies and public health activities.

  • EU/EEA
  • Surveillance
  • Variant Creutzfeldt-Jakob disease (vCJD)

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