Public health guidance: Seasonal influenza vaccination of children and pregnant women
The aim of this guidance document is to provide EU/EEA Member States and EU bodies with relevant information to make an informed decision on routine vaccination of healthy children and pregnant women with seasonal influenza vaccine. The options presented in this document are based on a systematic review of the literature and the opinions of a group of independent experts.
Effectiveness of rotavirus vaccination: Generic study protocols for retrospective case control and cohort studies based on computerised databases
In Europe, routine rotavirus vaccination of infants at the national level has been introduced with one or two vaccine brands in Finland, Austria, Luxembourg and Belgium within well-baby clinics or administered by general practitioners and paediatricians. When introducing a new vaccine, it is crucial to conduct studies evaluating the vaccination’s impact and effectiveness in order to decide on recommendations for its future use.
Seasonal influenza vaccination in Europe – Vaccination recommendations and coverage rates for 2012–13
This report provides an update on seasonal influenza immunisation policies and vaccination coverage rates in EU/EEA Member States for the 2012–13 influenza season.
Protocols for case-control studies to measure influenza vaccine effectiveness in the EU and EEA Member States
This publication presents the core European protocol for a series of proposed influenza vaccine effectiveness studies. The protocol includes a proposed plan for pooled analysis and has recently been adapted to measure vaccine effectiveness for the pandemic vaccine in 2009-10. Together with its twin publication ‘Protocols for cohort database studies to measure influenza vaccine effectiveness in the EU and EEA Member States’, this publication covers all methodological issues in the design and implementation of vaccine effectiveness studies, both for seasonal and the new A(H1N1)v influenza.
Seasonal influenza vaccination in Europe – Vaccination recommendations and coverage rates for 2013-14 and 2014-15
Overview of vaccination recommendations and coverage rates in the EU Member States for the 2013–14 and 2014–15 influenza seasons.
Assessing seasonal influenza vaccine effectiveness
On 3 December 2015, ECDC hosts a technical meeting to discuss influenza vaccine effectiveness studies and how they can best meet public health needs as well as regulatory requirements.
Efficacy and safety of single and double doses of Ivermectin versus 7-day high dose Albendazole for chronic StrongyloidiasisArchived
A prospective, randomized, open study was conducted in which a 7-day course of oral albendazole 800 mg daily was compared with a single dose (200 microgram/kilogram body weight) or double doses, given 2 weeks apart, of ivermectin in Thai patients with chronic strongyloidiasis.
Systematic review and meta-analysis concerning the efficacy and effectiveness of seasonal influenza vaccines – (part 1)Archived
This is an authoritative independent evidence-based review and meta-analysis of the efficacy and effectiveness of influenza vaccines. It confines itself to trials and observational studies where diagnostic tests confirmed influenza infection as the end point.
Systematic review and meta-analysis concerning the efficacy and effectiveness of seasonal influenza vaccines – (part 2)Archived
Systematic review and meta-analysis concerning the efficacy and effectiveness of seasonal influenza vaccines
The importance of analyses of antigenic match and monitoring influenza vaccine effectivenessArchived
Influenza viruses pose a particular challenge for those designing vaccines for humans. Much of the protective immunity that humans have against these viruses following natural infection or vaccination is due to immunological recognition of the haemagglutinin (HA) surface glycoprotein.