Carbapenem resistant Enterobacteriaceae - second update
Carbapenem resistance in Enterobacteriaceae such as Klebsiella pneumoniae and Escherichia coli poses a significant threat to patients and healthcare systems in all European Union/European Economic Area (EU/EEA) countries. Carbapenem-resistant Enterobacteriaceae (CRE) infections are associated with high mortality, primarily due to delays in administration of effective treatment and the limited availability of treatment options. Hypervirulent carbapenem-resistant K. pneumoniae strains have been reported presenting an additional threat with a potential for global dissemination. The spread of high risk clones and plasmids carrying carbapenemases in healthcare settings is a major cause of the spread of CRE in EU/EEA countries. Recent events of cross-border importation after patient transfer and large regional outbreaks as well as the worsening epidemiologic situation of carbapenemase-producing CRE in the EU/EEA highlight the high risk for further spread of CRE and the need for enhanced control efforts. Options for control are outlined in the respective section below.
Rapid risk assessment: Ebola virus disease outbreak in North Kivu and Ituri Provinces, Democratic Republic of the Congo - sixth update
This is the sixth update of a rapid risk assessment originally produced on 9 August 2018. The update addresses the impact of active chains of Ebola virus disease (EVD) transmission reported outside the outbreak’s epicentre, specifically in Goma, a provincial capital in the Democratic Republic of the Congo (DRC).
Rapid risk assessment: Ebola virus disease outbreak in North Kivu and Ituri Provinces, Democratic Republic of the Congo – fifth update
This is the fifth update of a rapid risk assessment originally produced on 9 August 2018. This rapid risk assessment addresses the potential public health impact of Ebola virus disease for EU/EEA countries and assesses the likelihood of international expansion.
Rapid risk assessment: Dengue outbreak in Réunion, France, and associated risk of autochthonous outbreak in the EU/EEA
This update of the risk assessment ‘Dengue outbreak in Réunion, France’ published on 5 July 2018, has been triggered by the significant size of the outbreak and its expected duration, which is anticipated to overlap with high vector activity in the southern EU.
Multi-country outbreak of Listeria monocytogenes clonal complex 8 infections linked to consumption of cold-smoked fish products
This joint ECDC-EFSA rapid outbreak assessment provides an assessment of the cross-border public health risk related to L. monocytogenes infections linked to the consumption of cold-smoked fish products, possibly originating from a single food processing company.
Rapid risk assessment: Regional outbreak of New Delhi metallo-betalactamase-producing carbapenem-resistant Enterobacteriaceae, Italy, 2018–2019
A large outbreak of New Delhi metallo-beta-lactamase (NDM)-producing carbapenem-resistant Enterobacteriaceae (CRE) has been reported from the Tuscany region in Italy. Between November 2018 and May 2019, seven Tuscan hospitals notified a total of 350 cases.
Risk assessment: Who is at risk of measles in the EU/EEA?
A large epidemic of measles has affected the EU/EEA Member States in the past three years, with 44 074 cases reported to ECDC by 30 Member States between 1 January 2016 and 31 March 2019.
Rapid risk assessment: Ebola virus disease outbreak in North Kivu and Ituri Provinces, Democratic Republic of the Congo – fourth update
This is the fourth update of a rapid risk assessment originally produced on 9 August 2018. This rapid risk assessment addresses the public health risk associated with the current Ebola virus outbreak in the DRC and its implications for EU/EEA citizens. It was triggered by an increase of EVD transmission in the affected areas over recent weeks, the persistent occurrence of new cases among contacts unknown at the time of EVD diagnosis, the occurrence of a substantial number of cases outside of the ring vaccination contacts and current challenges for the prevention and control of EVD.
Public consultation on HPV vaccines guidance opens
This guidance covers the following areas in relation to HPV vaccination: efficacy of the nine-valent HPV vaccine, HPV vaccination in people living with HIV and HPV vaccination in males and the cost-effectiveness of extending the HPV vaccination programme to include males.
Rapid outbreak assessment: Multi-country outbreak of Salmonella Poona infections linked to consumption of infant formula
This document provides an assessment of the cross-border public health risk related to the outbreak of Salmonella Poona infections in infants and young children linked to consumption of infant formula.