Public health guidance on use of interferon-gamma release assays in support of TB diagnosis
This report sets out the evidence on IGRAs and their use in the diagnosis of latent and active tuberculosis.After reviewing all available evidence, the expert panel concluded that ‘IGRAs should not replace the standard diagnostic methods for diagnosing active TB.’
Risk assessment: Laboratory-created A(H5N1) viruses transmissible between ferrets
The results of two, as yet unpublished, investigations of laboratory-induced genetic changes in avian influenza A(H5N1) viruses have been reported to have found that a surprisingly few number of changes make the viruses transmissible between ferrets, the most commonly used model for the way influenza behaves in humans. The possibility that this could have resulted in the development in laboratories of A(H5N1) influenza viruses transmissible between humans has caused concern for public safety and generated unusually high levels of debate in the scientific community. This report summarises and explains the complex public health and scientific issues around these developments including the positive and negative aspects of some of the responses that have been proposed internationally.
Rapid risk assessment: multidrug-resistant tuberculosis in migrants, multi-country cluster - 2nd update, 27 March 2017
This second update provides information regarding the risk of EU transmission of an MDR TB clone initially detected in seven asylum seekers from the Horn of Africa who currently reside in Switzerland.
Multidrug-resistant tuberculosis in migrants, multi-country cluster - 3rd update, 13 April 2017
A multi-country cluster of multidrug-resistant tuberculosis (MDR TB) involving 28 migrants has been delineated by whole genome sequencing (WGS) in migrants recently having arrived from countries in the Horn of Africa.