This is an authoritative independent evidence-based review and meta-analysis of the efficacy and effectiveness of influenza vaccines. It confines itself to trials and observational studies where diagnostic tests confirmed influenza infection as the end point.

​A rapid communication published on April 12th 2012 describes the early results of the annual multicentre case-control study undertaken by the ECDC sponsored I-MOVE consortium whose work is coordinated by an Epiconcept team

Influenza vaccine experts from thirteen EU countries and invited guests from Canada and the US gathered for three days July 1-3, 2013 in Annecy, France to report and discuss obtained national and pooled multi-country seasonal influenza vaccine effectiveness (VE) obtained in the 2012/2013 season. The meeting was co-organized by ECDC and Epiconcept.

The authors used a test-negative case control design to estimate the 2013/14 influenza vaccine effectiveness (VE) in patients seen with influenza-like illness as outpatients in Spain during December 2013-January 2014.

Preliminary results of European vaccine effectiveness study show decreased protective effect of the seasonal influenza vaccine in 2011/2012 season. ECDC Director Marc Sprenger calls for action.

Influenza vaccination coverage among high-risk groups has dropped in the European Region over the last seven years, and half the countries report a decrease in the number of vaccine doses available.