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Artesunate versus quinine in the treatment of severe falciparum malaria malaria in African children (AQUAMAT): an open-label, randomized trialArchived

ECDC comment - 24 Jan 2011

This paper describes the results of an open-label randomized trial, comparing the use of artesunate and quinine for the treatment of severe Plasmodium falciparum malaria in children in 11 African countries.

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  • Travellers' health

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Scientific advances – Intravenous artesunate for severe Malaria in Travelers, EuropeArchived

ECDC comment - 30 Apr 2011

This study describes the outcome of 25 travellers with severe malaria who returned from malaria-endemic regions and were treated at 7 centres in Europe with intravenous artesunate. Among these 25 patients, one child and 24 adults (mean ± SD age 44.1 ± 16.1 years), 10 patients received the dosing regimen for artesunate initially recommended by WHO and 11 received artesunate, 2.4 mg/kg/dose.

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