On 4 October 2017, Italy reported through the Early Warning and Response System (EWRS) the detection of four Plasmodium falciparum malaria cases in the Apulia region. Cases are 21 to 37-year-old men, originally from Africa. All stated that they had been in Italy for more than three months. Dates for onset of symptoms ranged from 20 to 27 September 2017. The cases are agricultural workers in Ginosa and Castellaneta. Malaria vectors such as Anopheles labranchiae and Anopheles superpictus are present in Italy.