This section contains the case definitions* for Acquired Immunodeficiency Syndrome (AIDS) and Human Immunodeficiency Virus (HIV) Infection
*Source: Commission Decision of 28/IV/2008 amending Decision 2002/253/EC laying down case definitions for reporting communicable diseases to the Community network under Decision No 2119/98/EC of the European Parliament and of the Council
Clinical Criteria (AIDS)
Any person who has any of the clinical conditions as defined in the European AIDS case definition for:
- Adults and adolescents > 13 years [1]
- Children < 13 years of age [2]
Laboratory Criteria (HIV)
Adults, adolescents and children aged = 18 months
At least one of the following three:
- Positive result of a HIV screening antibody test or a combined screening test (HIV antibody and HIV p24 antigen) confirmed by a more specific antibody test (e.g. Western blot)
- Positive result of 2 EIA antibody test confirmed by a positive result of a further EIA test
- Positive results on two separate specimens from at least one of the following three:
- Detection of HIV nucleic acid (HIV-RNA, HIV-DNA)
- Demonstration of HIV by HIV p24 antigen test, including neutralisation assay
- Isolation of HIV
Children aged <18 months
Positive results on two separate specimens (excluding cord blood) from at least one of the following three:
- Isolation of HIV
- Detection of HIV nucleic acid (HIV-RNA, HIV-DNA)
- Demonstration of HIV by HIV p24 antigen test, including neutralisation assay in a child =1 month of age
Epidemiological Criteria NA
Case Classification
A. Possible case
NA
B. Probable case
NA
C. Confirmed case
HIV infection
Any person meeting the laboratory criteria for HIV infection
AIDS
Any person meeting the clinical criteria for AIDS and the laboratory criteria for HIV infection
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1. European Centre for the Epidemiological Monitoring of AIDS. 1993 revision of the European AIDS surveillance case definition. AIDS Surveillance in Europe, Quarterly Report 1993; No. 37: 23-28
2. European Centre for the Epidemiological Monitoring of AIDS. European case definition for AIDS surveillance in children - revision 1995. HIV/AIDS Surveillance in Europe, Quarterly Report 1995; No. 48: 46-53